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g6pd activator ag1  (MedChemExpress)


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    Structured Review

    MedChemExpress g6pd activator ag1
    The intersection target <t>G6PD</t> promotes liver cancer metastasis and immune cell infiltration. (A) Predicted distribution of G6PD + malignant cells in HCC-1, HCC-2 L, HCC-2 T, and HCC-2P, respectively. (B) G6PD expression in normal tissues, liver cancer tissues, and metastatic tissues from TNMplot database. (C) Survival analysis of G6PD in HCCDB6, HCCDB15, and HCCDB25 datasets. (D) Survival analysis of G6PD in liver cancer from Kaplan–Meier Plotter database. (E) Overall survival of G6PD in LIHC from GEPIA2 database. (F) Correlational analyses of G6PD with VIM, CDH, and VEGFA, respectively in HCC. (G) Scatter of immune infiltrating cells and GPX8 expression level in in HCC. (H) Survival curves of OS between G6PD-high or -low and CD 8 + T cells infiltrating-high or -low patients with HCC.
    G6pd Activator Ag1, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 11 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/g6pd activator ag1/product/MedChemExpress
    Average 94 stars, based on 11 article reviews
    g6pd activator ag1 - by Bioz Stars, 2026-03
    94/100 stars

    Images

    1) Product Images from "Synergistic mechanism of Shengyang Shiyiwei Pill in enhancing bevacizumab efficacy for hepatocellular carcinoma-associated ascites"

    Article Title: Synergistic mechanism of Shengyang Shiyiwei Pill in enhancing bevacizumab efficacy for hepatocellular carcinoma-associated ascites

    Journal: Annals of Medicine and Surgery

    doi: 10.1097/MS9.0000000000004420

    The intersection target G6PD promotes liver cancer metastasis and immune cell infiltration. (A) Predicted distribution of G6PD + malignant cells in HCC-1, HCC-2 L, HCC-2 T, and HCC-2P, respectively. (B) G6PD expression in normal tissues, liver cancer tissues, and metastatic tissues from TNMplot database. (C) Survival analysis of G6PD in HCCDB6, HCCDB15, and HCCDB25 datasets. (D) Survival analysis of G6PD in liver cancer from Kaplan–Meier Plotter database. (E) Overall survival of G6PD in LIHC from GEPIA2 database. (F) Correlational analyses of G6PD with VIM, CDH, and VEGFA, respectively in HCC. (G) Scatter of immune infiltrating cells and GPX8 expression level in in HCC. (H) Survival curves of OS between G6PD-high or -low and CD 8 + T cells infiltrating-high or -low patients with HCC.
    Figure Legend Snippet: The intersection target G6PD promotes liver cancer metastasis and immune cell infiltration. (A) Predicted distribution of G6PD + malignant cells in HCC-1, HCC-2 L, HCC-2 T, and HCC-2P, respectively. (B) G6PD expression in normal tissues, liver cancer tissues, and metastatic tissues from TNMplot database. (C) Survival analysis of G6PD in HCCDB6, HCCDB15, and HCCDB25 datasets. (D) Survival analysis of G6PD in liver cancer from Kaplan–Meier Plotter database. (E) Overall survival of G6PD in LIHC from GEPIA2 database. (F) Correlational analyses of G6PD with VIM, CDH, and VEGFA, respectively in HCC. (G) Scatter of immune infiltrating cells and GPX8 expression level in in HCC. (H) Survival curves of OS between G6PD-high or -low and CD 8 + T cells infiltrating-high or -low patients with HCC.

    Techniques Used: Expressing

    SYP-medicated serum increased sorafenib sensitivity of HepG2 cells through G6PD. (A–D) G6PD expression in liver tissues with different sorafenib response status and the ROC curve of G6PD in predicting the response status of sorafenib. (E) The expression of G6PD and GPX4 protein were detected by Western blot. (F) CCK8 assays of SYP containing serum on sensibility of HepG2 to sorafenib.
    Figure Legend Snippet: SYP-medicated serum increased sorafenib sensitivity of HepG2 cells through G6PD. (A–D) G6PD expression in liver tissues with different sorafenib response status and the ROC curve of G6PD in predicting the response status of sorafenib. (E) The expression of G6PD and GPX4 protein were detected by Western blot. (F) CCK8 assays of SYP containing serum on sensibility of HepG2 to sorafenib.

    Techniques Used: Expressing, Western Blot

    Molecular docking of compounds with target protein G6PD. (A) Quercetin. (B) Kaempferol. (C) Beta-Sitosterol. (D) Apigenin. (E) Oleic acid.
    Figure Legend Snippet: Molecular docking of compounds with target protein G6PD. (A) Quercetin. (B) Kaempferol. (C) Beta-Sitosterol. (D) Apigenin. (E) Oleic acid.

    Techniques Used:



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    Image Search Results


    The intersection target G6PD promotes liver cancer metastasis and immune cell infiltration. (A) Predicted distribution of G6PD + malignant cells in HCC-1, HCC-2 L, HCC-2 T, and HCC-2P, respectively. (B) G6PD expression in normal tissues, liver cancer tissues, and metastatic tissues from TNMplot database. (C) Survival analysis of G6PD in HCCDB6, HCCDB15, and HCCDB25 datasets. (D) Survival analysis of G6PD in liver cancer from Kaplan–Meier Plotter database. (E) Overall survival of G6PD in LIHC from GEPIA2 database. (F) Correlational analyses of G6PD with VIM, CDH, and VEGFA, respectively in HCC. (G) Scatter of immune infiltrating cells and GPX8 expression level in in HCC. (H) Survival curves of OS between G6PD-high or -low and CD 8 + T cells infiltrating-high or -low patients with HCC.

    Journal: Annals of Medicine and Surgery

    Article Title: Synergistic mechanism of Shengyang Shiyiwei Pill in enhancing bevacizumab efficacy for hepatocellular carcinoma-associated ascites

    doi: 10.1097/MS9.0000000000004420

    Figure Lengend Snippet: The intersection target G6PD promotes liver cancer metastasis and immune cell infiltration. (A) Predicted distribution of G6PD + malignant cells in HCC-1, HCC-2 L, HCC-2 T, and HCC-2P, respectively. (B) G6PD expression in normal tissues, liver cancer tissues, and metastatic tissues from TNMplot database. (C) Survival analysis of G6PD in HCCDB6, HCCDB15, and HCCDB25 datasets. (D) Survival analysis of G6PD in liver cancer from Kaplan–Meier Plotter database. (E) Overall survival of G6PD in LIHC from GEPIA2 database. (F) Correlational analyses of G6PD with VIM, CDH, and VEGFA, respectively in HCC. (G) Scatter of immune infiltrating cells and GPX8 expression level in in HCC. (H) Survival curves of OS between G6PD-high or -low and CD 8 + T cells infiltrating-high or -low patients with HCC.

    Article Snippet: Sorafenib (HY-10201), Fluasterone (HY-106328), and G6PD activator AG1 (HY-123962) were obtained from MedChemExpress.

    Techniques: Expressing

    SYP-medicated serum increased sorafenib sensitivity of HepG2 cells through G6PD. (A–D) G6PD expression in liver tissues with different sorafenib response status and the ROC curve of G6PD in predicting the response status of sorafenib. (E) The expression of G6PD and GPX4 protein were detected by Western blot. (F) CCK8 assays of SYP containing serum on sensibility of HepG2 to sorafenib.

    Journal: Annals of Medicine and Surgery

    Article Title: Synergistic mechanism of Shengyang Shiyiwei Pill in enhancing bevacizumab efficacy for hepatocellular carcinoma-associated ascites

    doi: 10.1097/MS9.0000000000004420

    Figure Lengend Snippet: SYP-medicated serum increased sorafenib sensitivity of HepG2 cells through G6PD. (A–D) G6PD expression in liver tissues with different sorafenib response status and the ROC curve of G6PD in predicting the response status of sorafenib. (E) The expression of G6PD and GPX4 protein were detected by Western blot. (F) CCK8 assays of SYP containing serum on sensibility of HepG2 to sorafenib.

    Article Snippet: Sorafenib (HY-10201), Fluasterone (HY-106328), and G6PD activator AG1 (HY-123962) were obtained from MedChemExpress.

    Techniques: Expressing, Western Blot

    Molecular docking of compounds with target protein G6PD. (A) Quercetin. (B) Kaempferol. (C) Beta-Sitosterol. (D) Apigenin. (E) Oleic acid.

    Journal: Annals of Medicine and Surgery

    Article Title: Synergistic mechanism of Shengyang Shiyiwei Pill in enhancing bevacizumab efficacy for hepatocellular carcinoma-associated ascites

    doi: 10.1097/MS9.0000000000004420

    Figure Lengend Snippet: Molecular docking of compounds with target protein G6PD. (A) Quercetin. (B) Kaempferol. (C) Beta-Sitosterol. (D) Apigenin. (E) Oleic acid.

    Article Snippet: Sorafenib (HY-10201), Fluasterone (HY-106328), and G6PD activator AG1 (HY-123962) were obtained from MedChemExpress.

    Techniques:

    (A) Lungs from mice were collected 24h post-infection and stained for TUNEL. Scale 600um. (B) Percentage of TUNEL-positive areas calculated in the left lobe using high-resolution photomicrographs. n = 2-6 mice/group. * p < 0.05 using unpaired t-test. (C-E) G6PD enzyme activity assayed in Bronchoalveolar lavage (BAL) realized at 6h, 24h and 72h post-infection. n = 5-10 mice/group. * p < 0.05, *** p < 0.0001 using unpaired t-test.

    Journal: bioRxiv

    Article Title: Furin Inhibition Protects Against Acute Lung Injury in a Mouse Model of Pseudomonas Aeruginosa Infection

    doi: 10.1101/2025.09.25.678606

    Figure Lengend Snippet: (A) Lungs from mice were collected 24h post-infection and stained for TUNEL. Scale 600um. (B) Percentage of TUNEL-positive areas calculated in the left lobe using high-resolution photomicrographs. n = 2-6 mice/group. * p < 0.05 using unpaired t-test. (C-E) G6PD enzyme activity assayed in Bronchoalveolar lavage (BAL) realized at 6h, 24h and 72h post-infection. n = 5-10 mice/group. * p < 0.05, *** p < 0.0001 using unpaired t-test.

    Article Snippet: Glucose-6-phosphate dehydrogenase (G6PD) level was measured using CyQUANTTM Cytotoxicity Assay kit (V23111, Invitrogen).

    Techniques: Infection, Staining, TUNEL Assay, Activity Assay